Indications for plasmapheresis

Plasmapheresis - the name of the procedure with the help ofwhich purify the blood plasma. This universal method can be used in diseases of different origin. As a result, the body is removed from plasmapheresis certain volume of blood plasma.

The therapeutic effect of the procedure

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Blood can be divided into two components: liquid and cellular. The cellular component is represented by the formed elements of the blood (erythrocytes, white blood cells and platelets), and the liquid component is represented directly by the plasma, which consists of protein and saline solutions, and there are compounds that are dangerous to the body.

The plasmapheresis procedure has a pronouncedtherapeutic effect: when a part of the plasma is removed, the patient’s organism is also left by harmful substances that caused a particular disease. Cholesterol, uric acid, pathological proteins, and products of protein breakdown are considered to be such “pests”. Affected organs and their systems will begin to function better as soon as the patient's blood quality indicators increase. In addition, one more positive side of plasmapheresis can be noted: as a result of mechanical purification of the blood from harmful toxins, the body forms a response - mobilizes its defenses.

Most often, the composition include plasmapheresiscomplex therapy, as its use as an independent procedure, does not always produce visible results, and the effect lasts for long. Mechanical blood purification method combined, usually with such therapeutic procedures that do not allow blood partially saturated toxins formation of dangerous compounds in the body, and also stimulate them to flow freely from the body.

The methods of the procedure

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The list of pathologies in which the patient showsplasmapheresis, is very extensive, and our website reiterates that a stable positive effect after such a cleaning procedure is observed only in combination with other therapeutic methods. Mechanical cleaning of the blood is advisable to apply for the following diseases and conditions:

  • multiple myeloma;
  • massive destruction of red blood cells inside the vessels;
  • free myoglobin in the blood;
  • hemoglobinopathies;
  • intoxication with poisons of chemical origin;
  • porphyria;
  • myasthenia gravis;
  • Gasser's disease.

Mechanical cleaning of the blood and has a beneficial effect on the patient in such diseases:

Contraindications to the procedure

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Unfortunately, even this useful at firstopinion procedure as plasmapheresis, has side effects. The idea is that in the blood plasma and leave the body useful for the organism substances: proteins (including immunoglobulins) and components of blood coagulation (prothrombin, fibrinogen). On this basis, a blood purification is not performed if the patient diagnosed with low levels of protein in the blood, as well as a high probability of bleeding (usually happens if severely impaired liver).

Contraindications to plasmapheresis is divided into absolute and relative.

Absolute contraindications include severe damage to vital organs (brain, heart, lung, kidney or liver disease), massive bleeding.

Relative contraindications considered high bleeding and high risk of bleeding on the basis of a variety of diseases (for example, stomach ulcers and 12 duodenal ulcer), lack of stability in the circulatory system (hypotension), low concentration of protein in the blood, diseases of infectious origin, pregnancy and menstruation.

Here are the absolute contraindications for plasmapheresis:

  1. Overloading of the cardiovascular system (in particular the right heart).
  2. Pathological death of brain vessels due to cerebrovascular accidents.
  3. Excessive increase in blood pressure.
  4. Drug addiction and other psychological disorders.
  5. Anemia.
  6. Too thick blood.
  7. Acute or chronic liver dysfunction.

Session blood purification in the presence of these diseases can result in patient death.

Another controversy is the question on the use of plasmapheresis for the patient to get rid of alcohol addiction. While using this procedure and can bring alcohol from the blood after some time will inevitablydeveloping withdrawal symptoms, expressed some neuropsychiatric disorders, disorders of the cardiovascular system, brain edema, liver dysfunction. In short, to use plasmapheresis to treat addicted patients is impractical and dangerous to patients' lives. Alcoholism and drug addiction ksenonoterapiey respond well to treatment.

Possible complications of the procedure

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Experience has shown that the human body, inthat there are no contraindications to plasmapheresis, can respond to this method of blood purification completely unpredictable manner. Here are some complications manifested in patients as a result of the treatment:

  1. Anaphylactic shock. An allergic reaction manifested by chills, various autonomic disorders, haemodynamic disturbances and leads to death in 60% of cases.
  2. Hypotension. Blood pressure is sharply reduced, which leads to oxygen deficiency in the brain. About 60% of cases end in a lifelong disability or death.
  3. Extensive bleeding (when erosion and ulcers of the intestine), which is sometimes very difficult to stop, so the patient quickly revived. single fatal cases have been reported.
  4. The citrate intoxication. It happens rarely - the patient goes into a coma and dies.

Special training to mechanical blood purification procedure is not provided, as well as there are no specific recommendations after the conference.

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